2011-2013 Established Dongshengyuan Research Institute focusing on cosmetic R&D 2014 Shanghai Yuanben Skincare Co., Ltd., focusing on maternity & infant skincare, founded 2015-2017 Dedicated to developing products suited to Chinese skin and building a benchmark in light medical beauty skincare
ABOUT BIO-TIDE
R&D-Driven Skincare Manufacturing
BIO-TIDE integrates formula development, testing, packaging coordination, compliance support and manufacturing into one skincare development system.
We help skincare brands turn product concepts into stable, scalable and market-ready products.

BIO-TIDE Timeline
2018 oint Laboratory with Korea Institute of Skin Science — Dongshengyuan Research Institute officially launched Strategic Partner of China Beauty Expo 2019 Partnered with global top suppliers for imported raw materials from the US, Germany, France and beyond.
2020 Awarded Excellent Innovative R&D Team at China Cosmetic Technology Festival 2021 Strategic cooperation with Japan Hanajirushi; launched Asian Skin Science Program and built Asian Skin Property Database BIO-TIDE Skin Science Research Institute founded with 34 exclusive patents
2022 In-house testing laboratory obtained CMA accreditation Certified by MIIT for Integration of Informatization & Industrialization, qualified for Grade-A cosmetic CRO managemen Cooperated with expert teams to develop exclusive fermented functional raw materials
2023 Guangdong Youxue Pharmaceutical Technology Co., Ltd. founded as our industrial manufacturing base Cooperated with Guangdong Provincial Institute of Chinese Medicine, owning multiple patents on plant sunscreen and preservatives Strategic cooperation with Guangdong Weilandi Medical Technology
2024 Cooperated with Fujian Special Food Association to draft national group standard for tremella polysaccharide Launched supply chain formula R&D project with Guangdong Radio & TV Transportation Group Appointed designated supplier of special products for China Railway Guangzhou Group
2025 Strategic cooperation with Beijing Tongrentang, ranked TOP1 within its supply chain Co-established Gene Skincare Research Institute together with Zhongzhi Biotech Guangdong Youxue Pharmaceutical Technology certified as High-tech Enterprise
FOUNDER & CHIEF FORMULATOR
Xie Kun
Founder, Chairman & Chief Formulator of BIO-TIDE, known as "Peptide Dad". He is a senior expert in China’s cosmetic industry. He owns 25 patents and one SCI paper, and is a pioneer of small-molecule peptide research. As one of China’s first generation of cosmetic formulators from CAS。
he boasts decades of technical experience. He works as a distinguished expert, visiting professor at multiple universities and Professor at Korea Institute of Skin Science. leading core research projects and taking technical roles in many cosmetic institutions.

Founder & Chief Formulator of BIO-TIDE. Trained under renowned industry experts Professor Xu Liang and dermatologist Liu Wei. With over 20 years of experience, he has served more than 600 brands and accumulated tens of thousands of mature skincare formulas.
We Have A Professional Team
Renowned Chinese Expert Advisors
Quickly responding to regulatory trends, we build world-class global R&D solutions supported by senior expert advisors.

Ma Laji
scientific advisor of Dr. Aier Skin Microecology
Professor, International Cosmetic College, Shanghai Institute of Technology A pioneer in skin microecology & skin epigenetics research, focusing on microecological skincare development.

Dr. Meng Hong
Professor of the School of Chemistry and Materials Engineering, Beijing Technology and Business University.
Director of the Key Laboratory of Light Industry Cosmetics of China. she has published more than 50 professional papers and serves as director of China Association of Chinese Medicine and chief physician at China Academy of Chinese Medical Sciences.

Dr. Zhao Hua
Director of the Cosmetics Department, Beijing Technology and Business University.
Vice Chairman of the Cosmetics Regulation Committee of China Drug Administration Research Society. He has published 3 monographs and over 50 papers, and presided over the formulation of 6 industry standards.

Dean An In-sook
Korea Institute of Skin Science.
PhD in Bioengineering and Professor of Fragrance & Cosmetic Science at Konkuk University. PhD in Bioengineering and Professor of Fragrance & Cosmetic Science at Konkuk University. Board member of the Asian Journal of Beauty and Cosmetics

Professor Mei Hexiang
Professor at the International Cosmetic College, Shanghai Institute of Technology.
Proponent of the precision skincare concept and founder of skincare brands. Initiator of the Cosmetics Committee of Chinese Pharmaceutical Association. Proponent of the precision skincare concept and founder of skincare brands.

Dr. Mao Yongjin
PhD in Biochemistry and Molecular Biology, Chinese Academy of Sciences.
Long engaged in research on camellia and soapberry plant extracts. Leader of botanical active ingredient projects.

Cross-Functional Expertise From Concept to Production
Our formulation, testing, production and project teams work together to align technical feasibility, quality requirements and launch schedules.
We deliver one-stop R&D solutions for emerging brands, professional skincare and Class II medical cosmetics, developing differentiated, safe and science-backed products.
生产优势
International Production Standards・Pharmaceutical-grade Quality Control

01 、 Packaging Material Testing
Before launch, new packaging materials undergo comprehensive tests including compatibility, sealing performance and stability. Incoming materials are inspected on texture, cleanliness and compression resistance to ensure safety and compliance.

02 、 Raw Material Inspection
Each batch of raw materials is tested for appearance, pH value, viscosity, active content, microorganisms and other indicators to guarantee safety, efficacy and reliability.

03、Semi-finished & Finished Product Testing
Every batch of semi-finished and finished products is tested for appearance, skin feel, stability and microorganisms to strictly control product quality..

04、Daily Monitoring of Ultra-pure Production Water
Adopting multi-stage ultra-pure water system with water quality superior to industry standards. Circulating water is disinfected by UV lamps and monitored daily to guarantee stable water quality.

05、Sanitation Control of High-standard GMP Workshop
We own a 100,000-class dust-free GMP workshop. Regular microbial monitoring on airborne bacteria, equipment and staff maintains high sanitation standards.。

06、Strict In-process Inspection & Complete Quality Traceability System
First article confirmation is required before mass production, with full-process inspection for each working procedure. Complete production records and sample library enable full-chain traceability for continuous quality improvement.
FREQUENT QUESTIONS

BIO-BITE commits to “empowering emerging brands with growth genes and empowering established brands with technological core strengths.”
Partner Brand Cases
Strong R&D strength relies on standardized production. Youxue runs a modern compliant factory, while BIO-TIDE delivers integrated R&D, testing and manufacturing. Adhering to cosmetic clean standards and rigorous quality control, we turn custom formulas into safe。
Professional Pet Fine Care Brand --沐森堂
Self-operated Brand by 15M All-Net Influencers ㅤㅤㅤ「肌蜜朵拉」
Professional Baby & Kids Care Brand--奇宝星
Contact Us
Send a message through the site form for the fastest routing, or contact us directly for time-sensitive order questions.
linweijie@biotide-lab.com
For product questions, order help, and wholesale requests.
Phone
+86 13530758995
Monday to Friday, 9:00-18:00 PT.
Office
6th Floor South, Zhuomei Building, No.61 South Fenghuang Road, Huadu District, Guangzhou City, Guangdong Province, P.R.China
Hours
Mon-Fri, 9:00-18:00 PT
Messages sent outside these hours are reviewed the next business day.














